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Berberines anti-inflammatory mechanisms in adipose tissue Chronic low-grade inflammation serves as a pathophysiological nexus linking obesity to metabolic comorbidities, including IR, T2DM, and CVD [181, 183, 184]
NNMT plays a key role in regulating energy metabolism and fat storage
1 Even in darkness, the retina consumes large amounts of oxygen-often more than it does in light-making it particularly vulnerable to oxidative damage
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